Modified hCFTR mRNA restores normal lung function in a mouse model of cystic fibrosis
AKM Ashiqul Haque, Alexander Dewerth, Justin S. Antony, Joachim Riethmüller, Ngadhnjim Latifi, Hanzey Yasar, Petra Weinmann, Nicoletta Pedemonte, Elvira Sondo, Julie Laval, Patrick Schlegel, Christian Martin Seitz, Brigitta Loretz, Claus‐Michael Lehr, Rupert Handgretinger, Michael Kormann
This study shows that modified hCFTR mRNA delivered as nanoparticles improves lung function in a mouse model of cystic fibrosis.
bioRxiv · Oct 13, 2017 · PreprintGenetics