U1 snRNA blockade regulates DNA repair genes, DNA damage, and cisplatin sensitivity of lung cancer cells
Alexandre Devaux, Céline M. Labbé, Stéphan Vagner, Martin Dutertre
This study shows that blocking U1 snRNA increases cisplatin-induced DNA damage and sensitizes lung cancer cells to genotoxic agents by affecting DNA repair gene expression.
bioRxiv · Aug 28, 2026 · PreprintMolecular Biology