Author

Mandy Cadix

Université Paris-Sud

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:human· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Martin DutertreiD· 3 shared Nicolas ServantiD· 3 shared Stéphan VagneriD· 3 shared Caroline RobertiD· 2 shared Céline M. Labbé· 2 shared Didier AuboeufiD· 2 shared Galina BoldinaiD· 2 shared Pierre GestraudiD· 2 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersMolecular Biology

Martin DutertreORCID

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3 papers

Recent·Most cited

Intronic polyadenylation isoforms in the 5' part of genes constitute a source of microproteins and are involved in cell response to cisplatin

Alexandre Devaux, Iris Tanaka, Mandy Cadix, Amélie Heneman-Masurel, Sophie Michallet, Quentin Fouilleul, Alina Chakraborty, Céline M. Labbé, Nicolas Fontrodona, Jean‐Baptiste Claude, Marc Deloger, Pierre Gestraud, Ludovic Tessier, Hussein Mortada, Sonia Lameiras, , Martin Dutertre

The paper identifies microproteins encoded by intronic polyadenylation isoforms in the 5' part of genes and shows their role in modulating cisplatin response in cancer cells.

bioRxiv · Dec 5, 2023 · PreprintMolecular Biology

MET functions in tumour progression and therapy resistance are repressed by intronic polyadenylation

Galina Boldina, Maricarmen Vallejos, Delphine Allard, Mandy Cadix, Céline M. Labbé, Sophie Vacher, Oskar Hemmingsson, Pierre Gestraud, Aurélie Teissandier, Sylvain Martineau, Didier Auboeuf, Fabrice André, Maud T Kamal, Nicolas Servant, Ivan Bièche, , Stéphan Vagner

The paper shows that intronic polyadenylation (IPA) of MET affects tumour progression and therapy resistance by producing a short MET isoform that reduces invasiveness and enhances response to MAPK-targeted therapy.

bioRxiv · Aug 9, 2023 · PreprintMolecular Biology

Uncoupling from transcription protects polyadenylation site cleavage from inhibition by DNA damage

Rym Sfaxi, Biswendu Biswas, Galina Boldina, Mandy Cadix, Nicolas Servant, Huimin Chen, Daniel R. Larson, Martin Dutertre, Caroline Robert, Stéphan Vagner

The paper shows that post-transcriptional PAS cleavage of p53 pre-mRNA allows it to escape DNA damage inhibition, and identifies other DDR-related pre-mRNAs with similar mechanisms.

The EMBO Journal · Feb 10, 2023Peer-reviewedMolecular Biology