Minimally invasive activation of spared interneurons alleviates local CA1 hypersynchrony and behavioral deficits in a model of temporal lobe epilepsy
Célanie Matringhen, Alexandre Vigier, Nikoleta Bourtouli, François J. Michel, Thomas Marissal
This study investigates the role of Dlx-expressing interneurons in TLE, finding they are largely spared but show reduced activity, and that enhancing their activity can improve cognitive function.
Neurobiology of Disease · Oct 26, 2025Peer-reviewedNeuroscience