Author

Alexis Boleda

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Linn M. Gieser· 2 shared Alan M. Kwong· 1 shared Alexander J. Brucker· 1 shared Anand SwaroopiD· 1 shared Angel M. AponteiD· 1 shared Angela Jane CreeiD· 1 shared Anton Orlin· 1 shared Anupam Kumar MondaliD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Linn M. Gieser

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2 papers

Recent·Most cited

Distinctive cross-ancestry genetic architecture for age-related macular degeneration

Bryan R. Gorman, Georgios Voloudakis, Robert P. Igo, Tyler G. Kinzy, Christopher W. Halladay, Tim B. Bigdeli, Biao Zeng, Sanan Venkatesh, Jessica N. Cooke Bailey, Dana C. Crawford, Kyriacos Markianos, Frederick N. Dong, Patrick A. Schreiner, Wen Zhang, VA Million Veteran Program, , Srinivas V. Goverdhan

This study identifies 63 AMD risk loci across multiple ancestries, highlighting ancestry-dependent genetic heterogeneity and potential therapeutic targets.

Nature Genetics · Dec 1, 2024Peer-reviewedGenetic & Genomic Medicine

Early mitochondrial stress and metabolic imbalance lead to photoreceptor cell death in retinal degeneration

Ke Jiang, Anupam Kumar Mondal, Yogita K. Adlakha, Jessica Gumerson, Angel M. Aponte, Linn M. Gieser, Jung-Woong Kim, Alexis Boleda, Matthew J. Brooks, Jacob K. Nellissery, Donald A. Fox, Robert S. Balaban, Raúl Covián, Anand Swaroop

This study identifies early mitochondrial stress and metabolic imbalances as key drivers of photoreceptor cell death in retinal degeneration using a multi-omics approach in a mouse model.

bioRxiv · Oct 10, 2021 · PreprintNeuroscience