Multimodal profiling establishes ovarian fibrosis as a measurable and targetable hallmark of human reproductive aging
Lydia M. Hughes, Emily Zaniker-Gomez, Pooja Raj Devrukhkar, Subhasri Biswas, Alexis Trofimchuk, Tomiris Atazhanova, Joan K. Riley, Anna Kleinhans, Man Zhang, Signe Holm Nielsen, Morten Karsdal, Michael B. Stout, Elnur Babayev, Francesca E. Duncan
The paper integrates multimodal techniques to show ovarian fibrosis is a measurable and targetable feature of human reproductive aging.
bioRxiv · Sep 8, 2026 · PreprintCell Biology