Author

Anna Kleinhans

Northwestern Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Elnur BabayeviD· 4 shared Joan K. Riley· 4 shared Dilan GokyeriD· 3 shared Francesca E. DuncaniD· 2 shared Monica M. LarondaiD· 2 shared Alexis Trofimchuk· 1 shared Amanda WuiD· 1 shared Bervis HemişiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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4 shared papersDevelopmental Biology

Elnur BabayevORCID

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Author profile →

4 papers

Recent·Most cited

AAV-DJ Enables Targeted Gene Modulation in Human Ovarian Cells

Natasha Salpeter, Dilan Gokyer, Bervis Hemiş, Amanda Wu, Elizabeth L. Tsui, Diane C. Saunders, Meredith Lohman, Anna Kleinhans, Joan K. Riley, Monica M. Laronda, Mazhar Adli, Viviana Gradinaru, Máté Borsos, Elnur Babayev

This study demonstrates that AAV-DJ efficiently and safely transduces human ovarian cells, enabling targeted gene modulation with significant knockdown of AMHR2 and TGF{beta}1.

bioRxiv · Sep 10, 2026 · PreprintDevelopmental Biology

Multimodal profiling establishes ovarian fibrosis as a measurable and targetable hallmark of human reproductive aging

Lydia M. Hughes, Emily Zaniker-Gomez, Pooja Raj Devrukhkar, Subhasri Biswas, Alexis Trofimchuk, Tomiris Atazhanova, Joan K. Riley, Anna Kleinhans, Man Zhang, Signe Holm Nielsen, Morten Karsdal, Michael B. Stout, Elnur Babayev, Francesca E. Duncan

The paper integrates multimodal techniques to show ovarian fibrosis is a measurable and targetable feature of human reproductive aging.

bioRxiv · Sep 8, 2026 · PreprintCell Biology

Phthalates are detected in the follicular fluid of adolescents and oocyte donors with associated changes in the cumulus cell transcriptome

Dilan Gokyer, Mary J. Laws, Anna Kleinhans, Joan K. Riley, Jodi Anne Flaws, Elnur Babayev

The paper detects higher phthalate levels in adolescents' follicular fluid compared to oocyte donors and links these levels to changes in cumulus cell transcriptomes.

bioRxiv · Apr 4, 2024 · PreprintDevelopmental Biology

The oocyte microenvironment is altered in adolescents compared to oocyte donors.

Dilan Gokyer, Sophia Akinboro, Luhan Tracy Zhou, Anna Kleinhans, Monica M. Laronda, Francesca E. Duncan, Joan K. Riley, Kara N. Goldman, Elnur Babayev

This study compares the molecular signatures of cumulus cells and follicular fluid between adolescents and oocyte donors, finding significant differences in gene expression and cytokine profiles.

Human Reproduction Open · Jan 1, 2024Peer-reviewedDevelopmental Biology