NeurosciencebioRxivPreprint
Engineered α-Synuclein-specific nanobody CAR iTregs restrain neuroinflammation and proteinopathy in Parkinson's disease mice
Alice Calderoni, Melania Nannoni, Giorgia Ruffini…·Vania Broccoli
This study develops Syn-specific CAR iTregs that reduce neuroinflammation and proteinopathy in PD mice by selectively targeting aggregated α-Synuclein.
DOI 10.64898/2026.08.21.746338