Author

Amber Elitz

Cincinnati Children's Hospital Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Systems Biology· 2 Developmental Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Organism:mouse· 4 Assay:bulk RNA-seq· 3 Approach:statistical model· 3 Research Focus:cell-cell communication· 2 Organism:human· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

Barbara ZhaoiD· 4 shared Kathleen C.S. CookiD· 4 shared William J. ZachariasiD· 4 shared Amanda L. ZachariasiD· 3 shared Andrea TóthiD· 3 shared Helen I. Warheit-NiemiiD· 3 shared Sharlene FernandesiD· 3 shared Abigail JaquishiD· 1 shared

Activity by Year

2026-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersSystems Biology

Barbara ZhaoORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Early cell autonomous and niche-mediated alveolar epithelial response to influenza infection in primary lung organoids

Amber Elitz, Sharlene Fernandes, Kathleen C.S. Cook, Helen I. Warheit-Niemi, Barbara Zhao, Andrea Tóth, Amanda L. Zacharias, William J. Zacharias

This study models early IAV infection in alveolar organoids, revealing conserved AT2 cell responses and uninfected cell state transitions driven by inflammation.

JCI Insight · Jul 2, 2026Peer-reviewedSystems Biology

Alveolar-Basal Intermediates Drive Pulmonary Fibrosis via Coordination of a Pro-Fibrotic Signaling Niche in Silicosis

Barbara Zhao, Helen I. Warheit-Niemi, Kathleen C.S. Cook, Lori B. Pitstick, Andrea Tóth, Amber Elitz, Francis X. McCormack, Amanda L. Zacharias, William J. Zacharias

The paper shows that alveolar-basal intermediates (ABI) drive pulmonary fibrosis by coordinating a pro-fibrotic signaling niche in silicosis.

bioRxiv · Jun 27, 2026 · PreprintSystems Biology

Cell fate specification during respiratory development requires ARID1A-containing canonical BAF complex activity

Hyunwook Lee, Abigail Jaquish, Sharlene Fernandes, Barbara Zhao, Amber Elitz, Kathleen Cook, Sarah Trovillion, Natalia Bottasso-Arias, Simon J. Y. Han, Samantha Goodwin, Nicholas X. Russell, Gerald Saunders, Amanda L. Zacharias, Samantha A. Brugmann, Jeffrey A. Whitsett, , William J. Zacharias

The paper shows that the ARID1A-containing BAF complex is essential for lung development, proximal-distal axis specification, and cell fate acquisition during respiratory development.

Nature Communications · Apr 21, 2026Peer-reviewedDevelopmental Biology

The chromatin remodeling complex PRC2 safeguards cell fate in alveolar epithelial type 2 cells

Helen I. Warheit-Niemi, Jessie Huang, Kathleen C.S. Cook, Konstantinos–Dionysios Alysandratos, Sharlene Fernandes, Payel Basak, Barbara Zhao, Eitan Vilker, Carlos Villacorta-Martín, Amber Elitz, Pushpinder Bawa, Andrea Tóth, Michael J. Herriges, Darrell N. Kotton, William J. Zacharias

This study shows that PRC2 maintains AT2 cell fate in the adult lung by preventing transitions to ABI and basal-like states, both in vitro and in vivo.

bioRxiv · Mar 9, 2026 · PreprintGenetics