Free fatty acid receptor 4 agonists stimulate insulin secretion via different mechanisms in mouse versus human islets
LAURA REININGER, Muhammad Rehman, Ryan Hart, SARAH FERRAGNE, Caroline CT Tremblay, Mélanie Éthier, Amelia Bouabcha, Michelle E. Kimple, Julien J. Ghislain, Mark O. Huising, Vincent Poitout
This study compares the mechanisms of FFAR4 agonist-induced insulin secretion in mouse and human islets, finding indirect effects in mice and direct effects in humans.
Endocrinology · Sep 26, 2026Peer-reviewedCell Biology