Controlled and orthogonal partitioning of large particles into biomolecular condensates
Fleurie M. Kelley, Anas Ani, Emily G Pinlac, Bridget Linders, Bruna Favetta, Mayur Barai, Yuchen Ma, Arjun Singh, Gregory L. Dignon, Yuwei Gu, Benjamin S. Schuster
This study demonstrates that large particles can be controlled and orthogonally partitioned into biomolecular condensates through strong particle-condensate interactions, using polymer nanoparticles with tailored surface chemistries.
Nature Communications · Apr 14, 2025Peer-reviewedBiophysics