Bioresorbable, Injectable In Situ-Formed Electroactive mRNA-Delivering Device for Precision Gene Therapy after Myocardial Infarction
Umut Aydemir, Sevilay Sahoglu Goktas, Upala Dasmahapatra, Amit Singh Yadav, Karin Hellman, Sumit Sumit, Fredrik Ek, Anders Arner, Anja Meissner, martin hjort, Roger Olsson
This paper develops an injectable, bioresorbable device for localized mRNA delivery to the heart after myocardial infarction, showing improved cardiac function and reduced remodeling in mice.
bioRxiv · Nov 2, 2026 · PreprintBioengineering