Author

Andre Revnew

The Ohio State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:metabolomics· 1

Frequent Co-Authors

Christopher M. HadadiD· 3 shared Craig A. McElroyiD· 3 shared Pratik ShriwasiD· 3 shared Sean EkinsiD· 3 shared Thomas R. LaneiD· 3 shared Abigail M. Noonchester· 1 shared Abigail Noonchester· 1 shared Brian Scarpitti· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersPharmacology & Toxicology

Christopher M. HadadORCID

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3 papers

Recent·Most cited

Human CYP1A2 metabolism of organophosphorus pesticides and nerve agent surrogates

Pratik Shriwas, Matthew Politeski, Brian Scarpitti, Andre Revnew, Thomas R. Lane, Sean Ekins, Christopher M. Hadad, Craig A. McElroy

This study investigates CYP1A2's role in metabolizing organophosphorus compounds and finds it selectively degrades thions and is inhibited by OP compounds, suggesting its potential as a bioscavenger.

bioRxiv · Oct 25, 2026 · PreprintPharmacology & Toxicology

Organophosphorus pesticide and nerve agent surrogate metabolism by human CYP3A4

Pratik Shriwas, Abigail M. Noonchester, Brian T. Scarpitti, Andre Revnew, Thomas R. Lane, Sean Ekins, Christopher M. Hadad, Craig A. McElroy

This study evaluates CYP3A4's metabolism of organophosphorus compounds and finds it preferentially metabolizes thions over oxons, with some compounds inhibiting CYP3A4 activity.

bioRxiv · Apr 27, 2026 · PreprintPharmacology & Toxicology

Human CYP2C9 metabolism of organophosphorus pesticides and nerve agent surrogates

Pratik Shriwas, Abigail Noonchester, Andre Revnew, Thomas R. Lane, Christopher M. Hadad, Sean Ekins, Craig A. McElroy

This study investigates how CYP2C9 metabolizes organophosphorus pesticides and nerve agents, finding that it preferentially metabolizes thions over oxons and that binding energy correlates with metabolism and inhibition.

Journal of Xenobiotics · Dec 19, 2025Peer-reviewedPharmacology & Toxicology