Author

Andrea Wittmann

German Cancer Research Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Assay:scRNA-seq· 3 Approach:deep learning· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Cornelis Martinus van TilburgiD· 3 shared David T. W. JonesiD· 3 shared Henrik KaessmanniD· 3 shared Ioannis SarropoulosiD· 3 shared Konstantin OkonechnikoviD· 3 shared Lena M. KutscheriD· 3 shared Mari SeppiD· 3 shared Mirjam Blattner-JohnsoniD· 3 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Cornelis Martinus van TilburgORCID

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Author profile →

3 papers

Recent·Most cited

A multi-omics atlas of human hindbrain development

Piyush K. Joshi, Mari Sepp, Ioannis Sarropoulos, Nils Trost, Konstantin Okonechnikov, Tetsuya Yamada, Céline Schneider, Julia Schmidt, Ashwyn A Perera, Andrea Wittmann, Mirjam Blattner-Johnson, Barbara C. Jones, Cornelis Martinus van Tilburg, Olaf Witt, Steven Lisgo, , Lena M. Kutscher

This paper creates a multi-omics atlas of human hindbrain development, revealing cellular diversity, regulatory programs, and disease relevance.

bioRxiv · Feb 9, 2026 · PreprintNeuroscience

Medulloblastoma oncogene aberrations are not involved in tumor initiation, but essential for disease progression and therapy resistance

Konstantin Okonechnikov, Piyush K. Joshi, Verena Körber, Anne Rademacher, Michele Bortolomeazzi, Jan‐Philipp Mallm, Jan Vaillant, Patricia Benites Goncalves da Silva, Britta Statz, Mari Sepp, Ioannis Sarropoulos, Tetsuya Yamada, Andrea Wittmann, Kathrin Schramm, Mirjam Blattner-Johnson, , Stefan Michael Pfister

The paper uses single-cell technologies to show that large-scale chromosomal aberrations drive medulloblastoma initiation, while single-gene oncogenic events like MYC contribute to progression and therapy resistance.

Nature · May 7, 2025Peer-reviewedCancer Biology

Cell-state plasticity drives heterogeneity in Group 3/4 medulloblastoma

Piyush K. Joshi, Patricia Benites Goncalves da Silva, Konstantin Okonechnikov, Tamina Stelzer, Ioannis Sarropoulos, Mari Sepp, Jana Nolle, Mischan Vali Pour-Jamnani, Anne Rademacher, Tetsuya Yamada-Saito, Celine Schneider, Julia Schmidt, Luca Bianchini, Philipp Sven Lars Schäfer, Kevin Leiss, , Lena M. Kutscher

This study identifies cell-state plasticity as a driver of heterogeneity in Group 3/4 medulloblastomas, showing that transcription factor perturbation can redirect tumor cells along different differentiation trajectories.

bioRxiv · Feb 9, 2024 · PreprintCancer Biology