The BHMT-TET1 axis regulates glycolytic metabolism in oligodendrocytes and increases myelin in the EAE mouse model of multiple sclerosis
Marwan Shalih Maraicar, Sarah Sternbach, Morgan W. Psenicka, Katherine Knies, Ethan Lesco, Najmah Al Ramel, Andrew Eagar, Steven H. Zeisel, Ernest Johnson Freeman, Robert Clements, Jessica Lynn Williams, Jennifer Ann McDonough
The paper shows that activating the BHMT-TET1 pathway enhances oligodendrocyte metabolism and myelin production in an MS mouse model.
bioRxiv · Jul 27, 2026 · PreprintNeuroscience