Ku limits aberrant mRNA splicing promoted by intronic antisense Alu elements
Giovanni Pascarella, Madison P Turley, Mariia Mikhova, Gargi Parkhi, Jared Godfrey, Joshua Heyza, Tomáš Janovič, Li Han, Kefei Yu, Andrew Olive, Piero Carninci, Jens C. Schmidt, Katheryn Meek
The paper shows Ku prevents aberrant mRNA splicing caused by intronic antisense Alu elements, which affects RNA metabolism and cell viability.
bioRxiv · Nov 20, 2025 · PreprintMolecular Biology