Transcriptomic Analysis of Plac1 Ablation Reveals Broad Alterations in Signaling Pathways Essential for Prenatal Development and Overlap with a Preeclampsia-Associated Signature
Suzanne M. Jackman, Xiaoyuan Kong, Yulan Piao, Alexei A. Sharov, Elin Lehrmann, Andrew Varshine, Ramaiah Nagaraja, David Schlessinger, Michael E. Fant
This study uses gene expression microarrays to analyze placental gene expression changes in Plac1 knockout mice, identifying significant down- and upregulated genes and their involvement in developmental and preeclampsia-related pathways.
International Journal of Molecular Sciences · Aug 6, 2026Peer-reviewedDevelopmental Biology