Author

Anna Sorgente

Vita-Salute San Raffaele University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Emanuela FranchiniiD· 2 shared Giorgio CasariiD· 2 shared Irene SambriiD· 2 shared Katarína PAULÍKOVÁ· 2 shared Linda PattiniiD· 2 shared Angelo QuattriniiD· 1 shared Ilaria Marafelli· 1 shared Laura CassinaiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersNeuroscience

Emanuela FranchiniORCID

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2 papers

Recent·Most cited

Berberine improves motor deficits in the spastic paraplegia SPG7 mutant mice

Katarína PAULÍKOVÁ, Anna Sorgente, Emanuela Franchini, Paola Podini, Angelo Quattrini, Linda Pattini, Irene Sambri, Giorgio Casari

This study shows that berberine improves motor deficits in SPG7 mutant mice by modulating mitochondrial permeability transition pore dynamics.

bioRxiv · Jul 7, 2026 · PreprintNeuroscience

Pharmacological Restoration of Mitochondrial Permeability Transition Pore Flickering by High-Content Drug Repurposing

Emanuela Franchini, Matteo Bulloni, Anna Sorgente, Katarína PAULÍKOVÁ, Laura Cassina, Ilaria Marafelli, Irene Sambri, Linda Pattini, Giorgio Casari

This study identifies berberine as a compound that enhances mitochondrial permeability transition pore flickering, offering a potential therapeutic strategy for disorders like SPG7.

Pharmacological Research · May 7, 2026Peer-reviewedPharmacology & Toxicology