Molecular hallmarks of heterochronic parabiosis at single cell resolution
Róbert Pálovics, Andreas Keller, Nicholas Schaum, Weilun Tan, Tobias Fehlmann, Michael Borja, Fabian Kern, Liana N. Bonanno, Kruti Calcuttawala, James T. Webber, Aaron McGeever, Nicole Almanzar, Jane Antony, Ankit S. Baghel, Isaac Bakerman, , Rahul Sinha
This study uses single-cell RNA-sequencing to analyze cell type-specific responses to young or aged blood in heterochronic parabiosis, identifying mitochondrial function as a key factor in rejuvenation.
Nature · Mar 2, 2022Peer-reviewedGenomics