GeneticsbioRxivPreprint
Hyperactive intestinal proteolysis underlies smn-1 mutant phenotypes
Anusha Iyengar, Lindsey Philips, Adam D. Norris
The paper identifies intestinal proteolysis as the cause of smn-1 mutant phenotypes in C. elegans, showing that hyperactive proteasome activity and immune responses in the intestine drive disease.
DOI 10.64898/2026.08.11.744262