Disruption of the transcription factor NEUROD2 causes an autism syndrome via cell-autonomous defects in cortical projection neurons
Karen Runge, Rémi Mathieu, Stéphane Bugeon, Sahra Lafi, Corinne Beurrier, Surajit Sahu, Fabienne Schaller, Arthur Loubat, Léonard Hérault, Stéphane Gaillard, Mélanie Cahuc, Emilie Pallesi‐Pocachard, Aurélie Montheil, Andreas Bosio, Jill Anne Rosenfeld, , Antoine de Chevigny
This study identifies NEUROD2 mutations linked to ASD and intellectual disability, showing their role in cortical development and function through mouse models.
bioRxiv · Feb 14, 2020 · PreprintNeuroscience