Improving the Safety of N,N-Dimethylacetamide (DMA) as a Potential Treatment for Preterm Birth in a Pregnant Mouse Model Using a Vaginal Nanoformulation
Asad Mir, Teeshavi Acosta, Marta Concheiro, Steven M. Yellon, Ketan R. Patel, Sandra E. Reznik
This study compares vaginal and intraperitoneal dimethylacetamide formulations in a mouse model of preterm birth, finding similar efficacy but lower systemic concentrations with vaginal delivery.
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · Jan 20, 2025Peer-reviewedPharmacology & Toxicology