Pain Matters: Nociceptive signaling drives neural encoding of inflammatory responses
Megan Sammons, Rani Assa Polansky, Itay Zayalat, Samantha Breslauer Morris, Liwen Deng, Hilla Azulay-Debby, Neomi Singer, Isaac Chiu, Asya Rolls
The paper shows that nociceptive signaling is essential for the brain to represent and replay inflammatory states using human fMRI and mouse activity mapping.
bioRxiv · Nov 3, 2026 · PreprintNeuroscience