Author

Ayan Mohamed

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Addison Chen· 1 shared Andy Kwong· 1 shared Anneta Polakkottil· 1 shared B. Carbajal· 1 shared Benjamin R Butler· 1 shared Carla Marie PeraltaiD· 1 shared Cheng WangiD· 1 shared Chloe Tannous· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiochemistry

Addison Chen

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2 papers

Recent·Most cited

The Effects of Phosphorylation on the Structure and Function of Motif A, an Intrinsically Disordered Region within SIRT1

Sabrina M. Richter, Hoang-Long Bui, Addison Chen, Chloe Tannous, Benjamin R Butler, Sophia D Bennett, Samson Quang-anh Nguyen, Justin Prado, Ryan Nhan, Ayan Mohamed, Isaac A DuBois, Emile Tadros, Nhu Tam Thai, Selina Lima Guan, Carla Marie Peralta, , Ningkun Wang

This study investigates how phosphorylation affects the structure and function of motif A in SIRT1, showing that phosphomimetic mutation at Ser27 enhances SIRT1 activity and induces structural ordering of the disordered region.

Biochemistry · Jul 28, 2026Peer-reviewedBiochemistry

Hyperactivated YAP1 Drives an Invasive EMT Subtype of Cervical Squamous Cell Carcinoma

Jiyuan Liu, Xiangmin Lv, Jinpeng Ruan, Chunbo He, Guohua Hua, Peichao Chen, Xingeng Zhao, Davie Shi, Siyi Yang, Anneta Polakkottil, Madelyn L. Moness, B. Carbajal, Gunjan Kurma, Reema S. Guda, Ayan Mohamed, , Cheng Wang

This study identifies a YAP1-driven invasive cervical cancer subtype that evades HPV-based screening and shows it is associated with EMT and immunosuppressive myeloid cells.

bioRxiv · Jan 19, 2026 · PreprintCancer Biology