Shifts in mutation spectra enhance access to beneficial mutations
M. Sane, G. D. Diwan, B. A. Bhat, L. M. Wahl, D. Agashe
The paper shows that changing mutation spectra in E. coli increases beneficial mutations and reduces deleterious load, with simulations indicating that bias shifts are selectively favored.
bioRxiv · Sep 5, 2020 · PreprintEvolutionary Biology