Inhibition of Mycobacterium tuberculosis DosRST two-component regulatory system signaling by targeting response regulator DNA binding and sensor kinase heme
H. Zheng, B. Aleiwi, E. Ellsworth, R. B. Abramovitch
This study identifies two inhibitors of the Mtb DosRST regulatory system, showing they target different components of the pathway and reduce hypoxia-induced persistence.
bioRxiv · Sep 11, 2018Microbiology