B. C. de Jong

The paper identifies a new lineage of Mycobacterium tuberculosis complex, Lineage 8, found in the African Great Lakes region, and shows its evolutionary relationship to known lineages.

The paper compares the genomes of Mycobacterium africanum and Mycobacterium tuberculosis to identify mutations in electron transport and carbon metabolic pathways, suggesting adaptations to low oxygen environments.

This study evaluates the detection limits of rifampicin heteroresistance in four RDTs using mixed strains and Deeplex-MycTB, finding significant variation in sensitivity across tests.

The paper evaluates Xpert Ultra's ability to identify rifampicin resistance mutations by analyzing the relationship between rpoB mutations, Ultra probes, and melting temperature shifts.