Convergent clonal selection of donor- and recipient-derived CMV-specific T cells in hematopoietic stem cell transplant patients
J. R. Erickson, T. Stevens-Ayers, F. Mair, B. Edmison, M. Boeckh, P. H. Bradley, M. Prlic
The paper tracks T cell competition in CMV-reactivation post-transplant, finding donor-derived T cells expand but recipient-derived memory T cells remain dominant due to convergent clonal selection.
bioRxiv · Sep 14, 2021Immunology