Remodeling of human colon plasma cell repertoire in ulcerative colitis
J. F. Scheid, B. Eraslan, A. Hudak, E. Brown, D. Sergio, T. M. Delorey, D. Phillips, A. Lefkovith, A. T. Jess, L. W. Duck, C. O. Elson, H. Vlamakis, J. Deguine, A. A. Ananthakrishnan, D. B. Graham, , R. J. Xavier
This study characterizes the remodeling of the human colon plasma cell repertoire in ulcerative colitis, showing clonal expansion, isotype skewing, and altered gene expression associated with inflammation.
bioRxiv · Feb 14, 2022 · PreprintImmunology