BiochemistrybioRxivPreprint
Direct RNA sequencing reveals structural differences between transcript isoforms
A. J. G. Aw, S. Lim, J. X. Wang…·Y. Wan
This study introduces PORE-cupine, a method combining structure probing and nanopore sequencing to detect RNA secondary structures, revealing isoform-specific structural differences and their impact on translation efficiency.
DOI 10.1101/2020.06.11.147223