Spatial control of Keratin 8 phosphorylation by Aurora B facilitates cytokinesis in cancer cells of epithelial origin
B. Harmanda, H. Ayaydin, X. Waide, M. H. Qureshi, V. Basrur, A. I. Nesvizhskii, T. J. Mitchison, N. Ozlu
The paper shows Aurora B phosphorylates Keratin 8 at the cleavage furrow, facilitating its disassembly during cytokinesis in epithelial cancer cells.
bioRxiv · Jan 22, 2023Cell Biology