Acquired mutations and transcriptional remodeling in long-term estrogen-deprived locoregional breast cancer recurrences
N. Priedigkeit, K. Ding, W. Horne, J. K. Kolls, T. Du, P. C. Lucas, J.-U. Blohmer, C. Denkert, A. Machleidt, B. Ignold-Heppner, S. Oesterreich, A. V. Lee
This study analyzes acquired mutations and transcriptional changes in long-term estrogen-deprived breast cancer recurrences, identifying common genetic and expression alterations associated with endocrine resistance.
bioRxiv · Jun 8, 2020Cancer Biology