A RAB7A Phosphoswitch Coordinates Rubicon Homology Protein Regulation of PINK1/Parkin-Dependent Mitophagy
D. A. Tudorica, B. L. F. Basak, A. P. Cordova, G. Khuu, K. Rose, M. Lazarou, E. Holzbaur, J. H. Hurley
This study identifies a RAB7A phosphoswitch regulated by TBK1 that modulates Rubicon and Pacer interactions to control PINK1/Parkin-dependent mitophagy.
bioRxiv · Aug 28, 2023Cell Biology