The nucleoporin Nup50 activates the Ran guanyl-nucleotide exchange factor RCC1 to promote mitotic NPC assembly
G. Holzer, P. De Magistris, C. Gramminger, R. Sachdev, A. Magalska, A. Schooley, A. Scheufen, B. Lennartz, M. Tatarek-Nossol, H. Lue, M. I. Linder, U. Kutay, C. Preisinger, D. Moreno-Andres, W. Antonin
This study identifies Nup50's role in mitotic NPC assembly through its interaction with RCC1, independent of its nuclear transport function.
bioRxiv · Mar 31, 2021Cell Biology