Biogenesis of hepatitis B virus e antigen is driven by translocon-associated protein complex and regulated by conserved cysteines in signal peptide
H. Zabranska, A. Zabransky, B. Lubyova, J. Hodek, A. Krenkova, M. Hubalek, J. Weber, I. Pichova
The paper investigates the biogenesis of HBV e antigen, showing TRAP promotes its ER translocation and conserved cysteines regulate signal peptide cleavage and subcellular distribution.
bioRxiv · Jun 17, 2021Cell Biology