Allosteric mechanism of signal transduction in the two-component system histidine kinase PhoQ
B. Mensa, N. F. Polizzi, K. S. Molnar, A. M. Natale, T. Lemmin, W. F. DeGrado
The paper investigates how Mg2+ binding to the sensor domain of PhoQ modulates its kinase activity through allosteric communication between domains.
eLife · Dec 14, 2021Peer-reviewedBiochemistry