Structural basis for long-chain isoprenoids synthesis by cis-prenyltransferases
M. Giladi, M. Lisnyansky Bar-El, P. Vankova, A. Ferofontov, E. Melvin, D. Kavan, B. Redko, E. Haimov, R. Wiener, P. Man, Y. Haitin
This paper investigates the structural basis for long-chain isoprenoid synthesis by human cis-prenyltransferase, revealing a mechanism for directional product synthesis and membrane insertion.
bioRxiv · Oct 21, 2021Biochemistry