Interleukin-11 plays a key role in human and mouse alcohol-related liver disease
M. Effenberger, F. Grabherr, B. Schaefer, C. Grander, L. Mayr, J. Schwaerzler, B. Enrich, P. Moser, J. Fink, A. Pedrini, N. Jaschke, M. Freund, A. Loizides, R. Bale, D. Putzer, , H. Tilg
This study shows IL-11 is elevated in severe liver disease and blocking it reduces inflammation in alcohol-related liver disease in humans and mice.
bioRxiv · Aug 24, 2021 · PreprintImmunology