Simultaneous inhibition of human CD4 and 4-1BB biogenesis suppresses cytotoxic T lymphocyte proliferation
E. Claeys, E. Pauwels, S. Humblet-Baron, D. Schols, M. Waer, B. Sprangers, K. Vermeire
This study shows that CADA inhibits CD4 and 4-1BB expression, suppressing CD8+ T cell proliferation and cytotoxic activity in vitro.
bioRxiv · Dec 30, 2020Immunology