Exploring Mechanisms of Lipid Nanoparticle-Mucus Interactions in Healthy and Cystic Fibrosis Conditions
B. Tafech, M.-R. Rokhforouz, J. Leung, M. Sung, P. Lin, D. Sin, D. Lauster, S. Block, B. Quon, Y. Tam, P. Cullis, J. J. Feng, S. Hedtrich
This study investigates how lipid nanoparticles interact with mucus in healthy and cystic fibrosis conditions, identifying factors affecting their diffusivity for improved transmucosal delivery.
bioRxiv · Jan 18, 2024Bioengineering