Author

S. Block

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 2 Ecology· 2 Biochemistry· 1 Bioengineering· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 7 Organism:human· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:ecology & biodiversity· 2 Approach:microscopy & imaging analysis· 2 Organism:mouse· 2

Frequent Co-Authors

M. G. Vander Heiden· 2 shared A. A. Cluntun· 1 shared A. Balazs· 1 shared A. Blevins· 1 shared A. Bucharova· 1 shared A. Buttler· 1 shared A. Grafmueller· 1 shared A. Kocak· 1 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

M. G. Vander Heiden

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Cell surface RNA expression modulates alveolar epithelial function

J. K. Abledu, C. J. Herbst, R. Brandt, A. Kocak, P. Ghosh, J. L. G. Lopez, K. Diestelhorst, S. Block, C. Hackenberger, O. Seitz, E. Lopez-Rodriguez, M. Ochs, W. M. Kuebler

This study identifies glycoRNA as a novel component of the alveolar epithelial glycocalyx and shows its role in barrier regulation and viral infection.

bioRxiv · May 19, 2024Physiology

Reflection confocal microscopy for quantitative assessment of airway surface liquid dysregulation and pharmacological rescue in cystic fibrosis under near-physiological conditions

A. S. Agircan, M. Lampe, H. Scheuermann, T. Albrecht, S. Y. Graeber, A. Balazs, I. Baumann, S. Block, R. Pepperkok, M. A. Mall, J. Duerr

This paper introduces confocal reflection microscopy as a method to measure airway surface liquid height in cystic fibrosis models without perturbing the ASL, showing it is sensitive to detect ASL changes and therapeutic responses.

bioRxiv · Mar 5, 2024Cell Biology

Exploring Mechanisms of Lipid Nanoparticle-Mucus Interactions in Healthy and Cystic Fibrosis Conditions

B. Tafech, M.-R. Rokhforouz, J. Leung, M. Sung, P. Lin, D. Sin, D. Lauster, S. Block, B. Quon, Y. Tam, P. Cullis, J. J. Feng, S. Hedtrich

This study investigates how lipid nanoparticles interact with mucus in healthy and cystic fibrosis conditions, identifying factors affecting their diffusivity for improved transmucosal delivery.

bioRxiv · Jan 18, 2024Bioengineering

Photomanipulation of minimal synthetic cells: area increase, softening and interleaflet coupling of membrane models doped with azobenzene-lipid photoswitches

M. Aleksanyan, A. Grafmueller, F. Crea, V. N. Gergiev, N. Yandrapalli, S. Block, J. Heberle, R. Dimova

This study uses azobenzene-lipid photoswitches to manipulate membrane properties of synthetic cells using light, showing shape changes, softening, and altered electrical properties.

bioRxiv · Jan 3, 2023Biophysics

Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress

B. T. Do, P. P. Hsu, S. Y. Vermeulen, Z. Wang, T. Hirz, K. L. Abbott, N. Aziz, J. M. Replogle, S. Bjelosevic, J. Paolino, S. Nelson, S. Block, A. M. Darnell, R. Ferreira, H. Zhang, , M. G. Vander Heiden

The paper shows that nucleotide depletion and DNA replication stress drive cell fate transitions in hematopoietic systems by activating lineage-specific maturation genes.

bioRxiv · Aug 16, 2022Cancer Biology

Protein-Metabolite Interactomics Reveals Novel Regulation of Carbohydrate Metabolism

K. G. Hicks, A. A. Cluntun, H. L. Schubert, S. R. Hackett, J. A. Berg, P. G. Leonard, M. A. Ajalla Aleixo, A. Blevins, P. Barta, S. Tilley, S. Fogarty, J. M. Winter, H.-C. Ahn, K. N. Allen, S. Block, , J. Rutter

The paper develops the MIDAS platform to identify protein-metabolite interactions, revealing novel regulatory mechanisms in carbohydrate metabolism.

bioRxiv · Aug 28, 2021 · PreprintBiochemistry

Lowland plant arrival in alpine ecosystems facilitates a decrease in soil carbon content under experimental climate warming

T. W. N. Walker, K. Gavazov, T. Guillaume, T. Lambert, P. Mariotte, D. Routh, C. Signarbieux, S. Block, T. Muenkemueller, H. Nomoto, T. W. Crowther, A. Richter, A. Buttler, J. M. Alexander

The paper shows that introducing lowland plants into alpine ecosystems under warming increases soil carbon loss by enhancing root exudation and microbial respiration.

bioRxiv · Jul 21, 2021Ecology

Directed manipulation of membrane proteins by fluorescent magnetic nanoparticles

J. H. Li, P. Santos-Otte, B. Au, J. Rentsch, S. Block, H. Ewers

This study uses fluorescent magnetic nanoparticles to manipulate and track membrane proteins in live cells, revealing submembrane barriers linked to the actin cytoskeleton.

bioRxiv · Mar 30, 2020Biophysics

Effects of forest management on the phenology of early-flowering understory herbs

F. M. Willems, N. J. F. Scheepens, C. Ammer, S. Block, A. Bucharova, P. Schall, M. Sehrt, O. Bossdorf

The paper examines how forest management affects the flowering phenology of understory herbs, finding that higher management intensity delays flowering by about two weeks.

bioRxiv · Aug 15, 2019 · PreprintEcology