A simple method for developing lysine targeted covalent protein reagents
R. Gabizon, B. Tivon, R. N. Reddi, M. Van Den Oetelaar, H. Amartely, P. J. Cossar, C. Ottmann, N. London
This paper develops a method to create covalent protein reagents targeting lysine residues using methacrylate esters, demonstrating their effectiveness in binding and stabilizing protein complexes.
bioRxiv · Aug 28, 2023Biochemistry