Disease-associated mutations in WDR34 lead to diverse impacts on the assembly and function of dynein-2.
C. Shak, L. Vuolo, B. Uddin, Y. Katoh, T. Brown, A. G. Mukhopadhyay, K. Heesom, N. Stevenson, A. J. Roberts, K. Nakayama, D. Stephens
The study examines how disease-associated WDR34 mutations affect cilia assembly and function in a knockout cell model, revealing diverse phenotypic impacts.
Journal of Cell Science · Nov 7, 2022Peer-reviewedCell Biology