SARS-CoV-2 utilizes a multipronged strategy to suppress host protein synthesis
Y. Finkel, A. Gluck, R. Winkler, A. Nachshon, O. Mizrahi, Y. Lubelsky, B. Zuckerman, B. Slobodin, Y. Yahalom-Ronen, H. Tamir, I. Ulitsky, T. Israely, N. Paran, M. Schwartz, N. Stern-Ginossar
This study identifies how SARS-CoV-2 suppresses host protein synthesis through global translation reduction, mRNA degradation, and impaired translation of immune-related transcripts.
bioRxiv · Nov 25, 2020Microbiology