HIV-1 infection does not confer intrinsic resistance to cell death induced by cytotoxic T lymphocytes
Niklas Bachmann, Bailey Kim, Francesco Roberto Simonetti, Colin M Kovacs, Rebecca Hoh, Steven G. Deeks, Janet D'Angelo Siliciano, Robert F. Siliciano
The paper assesses whether HIV-1 infection confers resistance to CTL-mediated cell death and finds no intrinsic resistance, with survival differences attributed to MHC class I downregulation.
Journal of Clinical Investigation · Oct 29, 2026Peer-reviewedImmunology