A PATHWAY FOR T3 SIGNALING IN THE BRAIN TO IMPROVE THE VARIABLE EFFECTIVENESS OF THERAPY WITH L-T4
Federico Salas-Lucia, Csaba Fekete, Richárd Sinkó, Péter Egri, Kristóf Rada, Yvette Ruska, Barbara Bocco, Tatiana Fonseca, Balázs Gereben, Antonio Carlos Bianco
The paper identifies a neuronal pathway for T3 transport and signaling in the brain that explains variable L-T4 therapy effectiveness and resolves the paradox of T3 signaling amid high D3 activity.
eLife · May 19, 2023Peer-reviewedNeuroscience