High Dimensional Mediation Analysis: a new method applied to maternal smoking, placental DNA methylation and birth outcomes
Basile Jumentier, Claire-Cécile Barrot, Maxime Estavoyer, Jörg Tost, Barbara Heude, Olivier François, Johanna Lepeule
The paper develops HDMAX2, a method for high-dimensional mediation analysis, and applies it to study the indirect effects of maternal smoking on birth outcomes via placental DNA methylation.
Environmental Health Perspectives · Apr 1, 2023Peer-reviewedGenetic & Genomic Medicine