Patient-Specific Pharmacogenomics unveils xCT Regulation Pathways in Colon Cancer
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel E. Stange, Roland S. Croner, , Ulf D. Kahlert
This study identifies xCT regulation pathways in colon cancer using patient-specific models and reveals potential therapeutic targets for chemotherapy resistance.
bioRxiv · Feb 11, 2025 · PreprintCancer Biology