Kremen1 regulates the regenerative capacity of support cells and mechanosensory hair cells in the zebrafish lateral line
Ellen Megerson, Michael Kuehn, Ben Leifer, J. Bell, Julia L. Snyder, Hillary F. McGraw
This study shows that Kremen1 inhibits Wnt signaling and hair cell formation in zebrafish lateral line, and its absence leads to excessive regeneration through increased support cells when Wnt is overactivated.
iScience · Dec 7, 2023Peer-reviewedDevelopmental Biology