Automated structure refinement of macromolecular assemblies from cryo-EM maps using Rosetta
Ray Yu-Ruei Wang, Yifan Song, Benjamin Barad, Yifan Cheng, James Fraser, Frank DiMaio
This paper introduces an automated method to refine atomic structures from near-atomic-resolution cryo-EM maps, improving model geometry and fit-to-density while detecting and correcting backbone placement errors.
bioRxiv · Apr 26, 2016Biochemistry